Lin, Jiayuh : rechercher sur Z-Library

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1

11. Norepinephrine upregulates VEGF, IL-6, and IL-8 expression in human melanoma tumor cell lines: Implications for stress-related enhancement of tumor progression

Eric V. Yang, Seung-jae Kim, Elise L. Donovan, Min Chen, Amy Beickelman, Brian J. Hutzen, Jiayuh Lin, Sanford H. Barsky, Ronald Glaser

Journal:

Brain, Behavior, and Immunity

Année:

2008

Langue:

english

Fichier:

PDF, 38 KB

english, 2008

2

Structure–activity relationship studies of curcumin analogues

James R. Fuchs, Bulbul Pandit, Deepak Bhasin, Jonathan P. Etter, Nicholas Regan, Dalia Abdelhamid, Chenglong Li, Jiayuh Lin, Pui-Kai Li

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 515 KB

english, 2009

3

Reactivation of RASSF1A in Breast Cancer Cells by Curcumin

Du, Liping, Xie, Zhiliang, Wu, Lai-chu, Chiu, Ming, Lin, Jiayuh, Chan, Kenneth K., Liu, Shujun, Liu, Zhongfa

Journal:

Nutrition and Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 424 KB

english, 2012

4

Discovery of Novel STAT3 Small Molecule Inhibitors via in Silico Site-Directed Fragment-Based Drug Design

Yu, Wenying, Xiao, Hui, Lin, Jiayuh, Li, Chenglong

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.68 MB

english, 2013

5

Fragment-Based Drug Design and Drug Repositioning Using Multiple Ligand Simultaneous Docking (MLSD): Identifying Celecoxib and Template Compounds as Novel Inhibitors of Signal Transducer and Activator of Transcription 3 (STAT3)

Li, Huameng, Liu, Aiguo, Zhao, Zhenjiang, Xu, Yufang, Lin, Jiayuh, Jou, David, Li, Chenglong

Journal:

Journal of Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 2.03 MB

english, 2011

6

A Novel Small Molecular STAT3 Inhibitor, LY5, Inhibits Cell Viability, Cell Migration, and Angiogenesis in Medulloblastoma Cells

Xiao, Hui, Bid, Hemant Kumar, Jou, David, Wu, Xiaojuan, Yu, Wenying, Li, Chenglong, Houghton, Peter J., Lin, Jiayuh

Journal:

Journal of Biological Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 3.48 MB

english, 2015

7

Feedback Activation of STAT3 as a Cancer Drug-Resistance Mechanism

Zhao, Chengguang, Li, Huameng, Lin, Huey-Jen, Yang, Shulin, Lin, Jiayuh, Liang, Guang

Journal:

Trends in Pharmacological Sciences

Année:

2015

Langue:

english

Fichier:

PDF, 2.57 MB

english, 2015

8

Inhibition of IL-6/STAT3 signaling in human cancer cells using Evista

Shi, Wei, Yan, Dan, Zhao, Chongqiang, Xiao, Miaomiao, Wang, Yina, Ma, Haiyan, Liu, Tianshu, Qin, Hua, Zhang, Cuntai, Li, Chenglong, Lin, Jiayuh, Li, Sheng, Lv, Jiagao, Lin, Li

Journal:

Biochemical and Biophysical Research Communications

Année:

2017

Langue:

english

Fichier:

PDF, 1.66 MB

english, 2017

9

A novel small molecule STAT3 inhibitor, LY5, inhibits cell viability, colony formation, and migration of colon and liver cancer cells

Zhao, Chongqiang, Wang, Wenlong, Yu, Wenying, Jou, David, Wang, Yina, Ma, Haiyan, Xiao, Hui, Qin, Hua, Zhang, Cuntai, Lü, Jiagao, Li, Sheng, Li, Chenglong, Lin, Jiayuh, Lin, Li

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 3.86 MB

english, 2016

10

A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

Li Lin, Don M. Benson Jr., Stephanie DeAngelis, Courtney E. Bakan, Pui-Kai Li, Chenglong Li, Jiayuh Lin

Journal:

International Journal of Cancer

Année:

2012

Langue:

english

Fichier:

PDF, 891 KB

english, 2012

11

Design, synthesis, and studies of small molecule STAT3 inhibitors

Deepak Bhasin, Katryna Cisek, Trupti Pandharkar, Nicholas Regan, Chenglong Li, Bulbul Pandit, Jiayuh Lin, Pui-Kai Li

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2008

Langue:

english

Fichier:

PDF, 336 KB

english, 2008

12

Curcumin is a potent DNA hypomethylation agent

Zhongfa Liu, Zhiliang Xie, William Jones, Ryan E. Pavlovicz, Shujun Liu, Jianhua Yu, Pui-kai Li, Jiayuh Lin, Jame R. Fuchs, Guido Marcucci, Chenglong Li, Kenneth K. Chan

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2009

Langue:

english

Fichier:

PDF, 279 KB

english, 2009

13

Decreased Extracellular-Signal-Regulated Kinase and Increased Stress-Activated MAP Kinase Activities in Aged Human Skin In Vivo

Chung, Jin Ho, Kang, Sewon, Varani, James, Lin, Jiayuh, Fisher, Gary J., Voorhees, John J.

Journal:

The Journal of Investigative Dermatology

Année:

2000

Langue:

english

Fichier:

PDF, 454 KB

english, 2000

14

Dietary agent, benzyl isothiocyanate inhibits signal transducer and activator of transcription 3 phosphorylation and collaborates with sulforaphane in the growth suppression of PANC-1 cancer cells

Brian Hutzen, William Willis, Sarah Jones, Ling Cen, Stephanie Deangelis, Beng Fuh, Jiayuh Lin

Journal:

Cancer Cell International

Année:

2009

Langue:

english

Fichier:

PDF, 1.09 MB

english, 2009

15

XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells

Yan Liu, Aiguo Liu, Zhenghu Xu, Wenying Yu, Hong Wang, Chenglong Li, Jiayuh Lin

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 1.18 MB

english, 2011

16

New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells

Li Lin, Brian Hutzen, Sarah Ball, Elizabeth Foust, Matthew Sobo, Stephanie Deangelis, Bulbul Pandit, Lauren Friedman, Chenglong Li, Pui-Kai Li, James Fuchs, Jiayuh Lin

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.01 MB

english, 2009

17

Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells

Aiguo Liu, Yan Liu, Zhenghu Xu, Wenying Yu, Hong Wang, Chenglong Li, Jiayuh Lin

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 378 KB

english, 2011

18

Molecular Mechanisms of Photoaging in Human Skin In Vivo and Their Prevention by All-Trans Retinoic Acid

Gary J. Fisher, Harvinder S. Talwar, Jiayuh Lin, John J. Voorhees

Journal:

Photochemistry and Photobiology

Année:

1999

Langue:

english

Fichier:

PDF, 479 KB

english, 1999

19

Phosphorylation profiles of protein kinases in alveolar and embryonal rhabdomyosarcoma

Cen, Ling, Arnoczky, Kristy J, Hsieh, Fu-Chuan, Lin, Huey-Jen, Qualman, Stephen J, Yu, Songlin, Xiang, Huiyun, Lin, Jiayuh

Journal:

Modern Pathology

Année:

2007

Langue:

english

Fichier:

PDF, 602 KB

english, 2007

20

Inhibition of constitutively active Stat3 suppresses growth of human ovarian and breast cancer cells

Burke, William M, Jin, Xiaohong, Lin, Huey-Jen, Huang, Melinda, Liu, Rebecca, Reynolds, R Kevin, Lin, Jiayuh

Journal:

Année:

2001

Langue:

english

Fichier:

PDF, 313 KB

english, 2001

21

p53 regulates Stat3 phosphorylation and DNA binding activity in human prostate cancer cells expressing constitutively active Stat3

Lin, Jiayuh, Tang, Huaijing, Jin, Xiaohong, Jia, Guiyue, Hsieh, Jer-Tsong

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 239 KB

english, 2002

22

Stat3 upregulates MEK5 expression in human breast cancer cells

Song, Hui, Jin, Xiaohong, Lin, Jiayuh

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 298 KB

english, 2004

23

Constitutive Activation of Stat 3 Oncogene Product in Human Ovarian Carcinoma Cells

Melinda Huang, Carmen Page, R.Kevin Reynolds, Jiayuh Lin

Journal:

Gynecologic Oncology

Année:

2000

Langue:

english

Fichier:

PDF, 120 KB

english, 2000

24

Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice

Grace-Ifeyinwa Onimoe, Aiguo Liu, Li Lin, Chang-Ching Wei, Eric B. Schwartz, Deepak Bhasin, Chenglong Li, James R. Fuchs, Pui-kai Li, Peter Houghton, Amanda Termuhlen, Thomas Gross, Jiayuh Lin

Journal:

Investigational New Drugs

Année:

2012

Langue:

english

Fichier:

PDF, 709 KB

english, 2012

25

Systemic evaluation of total Stat3 and Stat3 tyrosine phosphorylation in normal human tissues

Chun-Liang Chen, Fu-Chuan Hsieh, Jiayuh Lin

Journal:

Experimental and Molecular Pathology

Année:

2006

Langue:

english

Fichier:

PDF, 930 KB

english, 2006

26

17-Allyamino-17-demethoxygeldanamycin and 17-NN-dimethyl ethylene diamine-geldanamycin have cytotoxic activity against multiple gynecologic cancer cell types

Dana R. Gossett, Megan S. Bradley, Xiaohong Jin, Jiayuh Lin

Journal:

Gynecologic Oncology

Année:

2005

Langue:

english

Fichier:

PDF, 452 KB

english, 2005

27

A small molecule compound inhibits AKT pathway in ovarian cancer cell lines

Huai-Jing Tang, Xiaohong Jin, Shaomeng Wang, Dajun Yang, Yeyu Cao, Jianyong Chen, Dana R. Gossett, Jiayuh Lin

Journal:

Gynecologic Oncology

Année:

2006

Langue:

english

Fichier:

PDF, 976 KB

english, 2006

28

The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines

Stacey L Fossey, Misty D Bear, Jiayuh Lin, Chenglong Li, Eric B Schwartz, Pui-Kai Li, James R Fuchs, Joelle Fenger, William C Kisseberth, Cheryl A London

Journal:

Année:

2011

Langue:

english

Fichier:

PDF, 3.20 MB

english, 2011

29

Signal transducer and activator of transcription 3 is involved in cell growth and survival of human rhabdomyosarcoma and osteosarcoma cells

Chun-Liang Chen, Abbey Loy, Ling Cen, Christina Chan, Fu-Chuan Hsieh, Gong Cheng, Bryant Wu, Stephen J Qualman, Keita Kunisada, Keiko Yamauchi-Takihara, Jiayuh Lin

Journal:

Année:

2007

Langue:

english

Fichier:

PDF, 1.22 MB

english, 2007

30

STAT3 can be activated through paracrine signaling in breast epithelial cells

Jacqueline C Lieblein, Sarah Ball, Brian Hutzen, A Kate Sasser, Huey-Jen Lin, Tim HM Huang, Brett M Hall, Jiayuh Lin

Journal:

Année:

2008

Langue:

english

Fichier:

PDF, 552 KB

english, 2008

31

New structural analogues of curcumin exhibit potent growth suppressive activity in human colorectal carcinoma cells

Ling Cen, Brian Hutzen, Sarah Ball, Stephanie DeAngelis, Chun-Liang Chen, James R Fuchs, Chenglong Li, Pui-Kai Li, Jiayuh Lin

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 1.16 MB

english, 2009

32

Characterization of STAT3 activation and expression in canine and human osteosarcoma

Stacey L Fossey, Albert T Liao, Jennifer K McCleese, Misty D Bear, Jiayuh Lin, Pui-Kai Li, William C Kisseberth, Cheryl A London

Journal:

Année:

2009

Langue:

english

Fichier:

PDF, 5.09 MB

english, 2009

33

Temperature-Sensitive Mutants of p53 Homologs

Radhika Pochampally, Changgong Li, Wenge Lu, Lihong Chen, Ronald Luftig, Jiayuh Lin, Jiandong Chen

Journal:

Biochemical and Biophysical Research Communications

Année:

2000

Langue:

english

Fichier:

PDF, 562 KB

english, 2000

34

Stat3 modulates heat shock 27 kDa protein expression in breast epithelial cells

Hui Song, Stephen P Ethier, Michele L Dziubinski, Jiayuh Lin

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 265 KB

english, 2004

35

Modulation of Janus kinase 2 by p53 in ovarian cancer cells

Thomas Reid, Xiaohong Jin, Hui Song, Huai-Jing Tang, R. Kevin Reynolds, Jiayuh Lin

Journal:

Biochemical and Biophysical Research Communications

Année:

2004

Langue:

english

Fichier:

PDF, 508 KB

english, 2004

36

Evaluation of potential Stat3-regulated genes in human breast cancer

Fu-Chuan Hsieh, Gong Cheng, Jiayuh Lin

Journal:

Biochemical and Biophysical Research Communications

Année:

2005

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2005

37

Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells

Suzanne Reed, Huameng Li, Chenglong Li, Jiayuh Lin

Journal:

Biochemical and Biophysical Research Communications

Année:

2011

Langue:

english

Fichier:

PDF, 992 KB

english, 2011

38

STAT3 signaling pathway is necessary for cell survival and tumorsphere forming capacity in ALDH+/CD133+ stem cell-like human colon cancer cells

Li Lin, James Fuchs, Chenglong Li, Veronica Olson, Tanios Bekaii-Saab, Jiayuh Lin

Journal:

Biochemical and Biophysical Research Communications

Année:

2011

Langue:

english

Fichier:

PDF, 727 KB

english, 2011

39

Altered trafficking of Fas and subsequent resistance to Fas-mediated apoptosis occurs by a wild-type p53 independent mechanism in esophageal adenocarcinoma1

Raja S. Mahidhara, Pierre E. Queiroz De Oliveira, Jaromir Kohout, David G. Beer, Jiayuh Lin, Simon C. Watkins, Paul D. Robbins, Steven J. Hughes

Journal:

Journal of Surgical Research

Année:

2005

Langue:

english

Fichier:

PDF, 467 KB

english, 2005

40

953 Epigenetic Silencing of NR4A3 and LOXL4 by Aberrant JAK/STAT Signaling Predicts Prognosis in Gastric Cancer

Li-Han Zeng, Liang-Yu Chang, Jian-Liang Chou, Alfred S. Cheng, Kun-Tu Yeh, Claudia Dittner, Jiayuh Lin, Michael W. Chan

Journal:

Gastroenterology

Année:

2012

Langue:

english

Fichier:

PDF, 64 KB

english, 2012

41

The Spectrum of Mutations at the p53 Locus : Evidence for Tissue-specific Mutagenesis, Selection of Mutant Alleles, and a “Gain of Function” Phenotype

ARNOLD J. LEVINE, MICHAEL C. WU, ANWELL CHANG, ABIGAIL SILVER, EDWARD F. ATTIYEH, JIAYUH LIN, CHARLES B. EPSTEIN

Journal:

Annals of the New York Academy of Sciences

Année:

1995

Langue:

english

Fichier:

PDF, 808 KB

english, 1995

42

Signal transducer and activator of transcription 3 activation is associated with bladder cancer cell growth and survival

Chun-Liang Chen, Ling Cen, Jennifer Kohout, Brian Hutzen, Christina Chan, Fu-Chuan Hsieh, Abbey Loy, Victor Huang, Gong Cheng, Jiayuh Lin

Journal:

Molecular Cancer

Année:

2008

Langue:

english

Fichier:

PDF, 1.47 MB

english, 2008

43

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity

Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson,

Journal:

Molecular Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 1.48 MB

english, 2010

44

A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells

Li Lin, Stephanie Deangelis, Elizabeth Foust, James Fuchs, Chenglong Li, Pui-Kai Li, Eric B Schwartz, Gregory B Lesinski, Don Benson, Jiagao Lü, Dale Hoyt, Jiayuh Lin

Journal:

Molecular Cancer

Année:

2010

Langue:

english

Fichier:

PDF, 2.95 MB

english, 2010

45

Biologic activity of the novel small molecule STAT3 inhibitor LLL12 against canine osteosarcoma cell lines

Jason I Couto, Misty D Bear, Jiayuh Lin, Michael Pennel…

Journal:

BMC Veterinary Research

Année:

2012

Langue:

english

Fichier:

PDF, 291 KB

english, 2012

46

Drug Design Targeting Protein–Protein Interactions (PPIs) Using Multiple Ligand Simultaneous Docking (MLSD) and Drug Repositioning: Discovery of Raloxifene and Bazedoxifene as Novel Inhibitors of IL-6/GP130 Interface

Li, Huameng, Xiao, Hui, Lin, Li, Jou, David, Kumari, Vandana, Lin, Jiayuh, Li, Chenglong

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.94 MB

english, 2014

47

A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells

Lin, Li, Hutzen, Brian, Li, Pui-Kai, Ball, Sarah, Zuo, Mingxin, DeAngelis, Stephanie, Foust, Elizabeth, Sobo, Matthew, Friedman, Lauren, Bhasin, Deepak, Cen, Ling, Li, Chenglong, Lin, Jiayuh

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 1.32 MB

english, 2010

48

IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-Induced STAT3 phosphorylation in human hepatocellular cancer cells

Liu, Yan, Fuchs, James, Li, Chenglong, Lin, Jiayuh

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 952 KB

english, 2010

49

Blocking the IL-6–STAT3 signaling pathway: potential liver cancer therapy

Liu, Yan, Lin, Jiayuh

Journal:

Future Oncology

Année:

2011

Langue:

english

Fichier:

PDF, 433 KB

english, 2011

50

Design, synthesis and evaluation of XZH-5 analogues as STAT3 inhibitors

Daka, Philias, Liu, Aiguo, Karunaratne, Chamini, Csatary, Erika, Williams, Cameron, Xiao, Hui, Lin, Jiayuh, Xu, Zhenghu, Page, Richard C., Wang, Hong

Journal:

Bioorganic & Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 1.13 MB

english, 2015